Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127090 | 0.80 | FGFR3 (0.81) | FGFR3 | |
| SCHEMBL1126675 | 0.71 | FGFR3 (0.80) | FGFR3 | |
| SCHEMBL12678227 | 0.71 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL17023101 | 0.70 | FGFR3 (0.64) | FGFR3 | |
| SCHEMBL1126244 | 0.70 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL1127041 | 0.67 | FGFR3 (0.62) | FGFR3 | |
| SCHEMBL12678228 | 0.67 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL1126299 | 0.64 | FGFR3 (0.70) | FGFR3 | |
| SCHEMBL1126308 | 0.63 | FGFR3 (0.78) | FGFR3 | |
| SCHEMBL1126459 | 0.62 | FGFR3 (0.84) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2011-02-16 | — | — | EP | claimed |