Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 16/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023023 | 0.90 | FGFR3 (0.63) | FGFR3FGFR1 | |
| SCHEMBL17023056 | 0.89 | FGFR3 (0.79) | FGFR3FGFR1 | |
| SCHEMBL1127090 | 0.89 | FGFR3 (0.81) | FGFR3 | |
| SCHEMBL17023160 | 0.89 | FGFR3 (0.80) | FGFR3 | |
| SCHEMBL17023105 | 0.85 | FGFR3 (0.79) | FGFR3 | |
| SCHEMBL17023154 | 0.80 | FGFR3 (0.65) | FGFR3FGFR1 | |
| SCHEMBL1126675 | 0.79 | FGFR3 (0.80) | FGFR3 | |
| SCHEMBL17023167 | 0.79 | FGFR3 (0.69) | FGFR3 | |
| SCHEMBL17023031 | 0.79 | FGFR3 (0.65) | FGFR3 | |
| SCHEMBL17023066 | 0.78 | FGFR3 (0.78) | FGFR3ALDH1A1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |