⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838849 | 0.70 | DPP4 (0.32) | — | |
| SCHEMBL10838840 | 0.70 | DPP4 (0.32) | — | |
| SCHEMBL11413446 | 0.61 | DPP4 (0.31) | — | |
| SCHEMBL23512951 | 0.58 | — | — | |
| SCHEMBL10837413 | 0.58 | — | — | |
| SCHEMBL10837419 | 0.58 | — | — | |
| SCHEMBL8956297 | 0.58 | — | — | |
| SCHEMBL23346768 | 0.56 | — | — | |
| SCHEMBL24385910 | 0.56 | MMP2 (0.33) | — | |
| SCHEMBL11956673 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062876-A1 | 2-Oxo-1-(((substituted sulfonyl)amino)carbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1982-10-20 | — | — | EP | disclosed |