Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276282 | 0.83 | MEN1 (0.43) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10761199 | 0.82 | TSHR (0.48) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL11743682 | 0.78 | KMT2A (0.42) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29727839 | 0.77 | TDP1 (0.56) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL27683829 | 0.77 | TDP1 (0.56) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10994442 | 0.77 | TDP1 (0.52) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9575258 | 0.76 | CYP1A2 (0.50) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL6645181 | 0.75 | TSHR (0.48) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29399544 | 0.74 | TDP1 (0.47) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22032838 | 0.74 | TDP1 (0.47) | TDP1TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054180-A2 | Process for the preparation of imidazoquinazoline derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-06-23 | — | — | EP | claimed |
| EP-0054180-A2 | Process for the preparation of imidazoquinazoline derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-06-23 | — | — | EP | disclosed |