Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.35 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.35 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.35 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.35 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.35 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265234 | 1.00 | HTT (0.48) | HTTLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL11263444 | 0.82 | HTT (0.71) | HTTLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL11263439 | 0.82 | HTT (0.71) | HTTLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL11305960 | 0.80 | HTT (0.46) | HTTLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL11309358 | 0.80 | HTT (0.46) | HTTLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL11250596 | 0.79 | MAOB (0.46) | HTTLMNAMAPTRAB9ANPC1 | |
| SCHEMBL11250592 | 0.79 | MAOB (0.46) | HTTLMNAMAPTRAB9ANPC1 | |
| SCHEMBL11269815 | 0.79 | PPARG (0.44) | HTTMAPTRAB9APOLBNPC1 | |
| SCHEMBL11262254 | 0.79 | LTA4H (0.43) | HTTLMNACYP1A2 | |
| SCHEMBL11262257 | 0.79 | LTA4H (0.43) | HTTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340765-A | 4-Phenoxy-2-butene derivatives as plant growth regulators | MALLINCKRODT BAKER, INC. | 1982-07-20 | — | — | US | disclosed |
| EP-0046282-A2 | 4-Phenoxy-2-butene derivatives and their use as plant growth regulators | J.T. Baker Chemical Co. (US) | 1982-02-24 | — | — | EP | disclosed |