Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.63 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249399 | 0.96 | LMNA (0.75) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11250079 | 0.93 | PIK3CD (0.73) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11249441 | 0.85 | LMNA (0.64) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11243884 | 0.85 | LMNA (0.72) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11242092 | 0.84 | LMNA (0.66) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11255375 | 0.84 | LMNA (0.60) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11255017 | 0.84 | LMNA (0.66) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11250379 | 0.84 | LMNA (0.66) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11243336 | 0.84 | LMNA (0.66) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11250034 | 0.84 | LMNA (0.66) | LMNAHTTSMN1; SMN2PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |