Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257241 | 0.93 | CYP2A6 (0.47) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11261083 | 0.90 | QPCT (0.45) | CYP19A1CYP11B1CYP11B2HMOX1ALDH1A1 | |
| SCHEMBL11265592 | 0.89 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL11262189 | 0.88 | CYP2A6 (0.50) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11262389 | 0.87 | CYP19A1 (0.44) | CYP19A1HMOX1 | |
| SCHEMBL11258554 | 0.86 | HMOX1 (0.50) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11267577 | 0.85 | CYP2A6 (0.41) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11265708 | 0.85 | CYP2A6 (0.48) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11259583 | 0.84 | HMOX1 (0.42) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11266452 | 0.84 | MAPK1 (0.41) | ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |