Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265305 | 0.89 | MEN1 (0.55) | MEN1KMT2ANR4A2MAPTLMNA | |
| SCHEMBL7110502 | 0.89 | MAOB (0.65) | MEN1KMT2ANR4A2MAPTLMNA | |
| SCHEMBL417705 | 0.88 | MAPT (0.60) | MEN1KMT2ANR4A2MAPTLMNA | |
| SCHEMBL21483677 | 0.88 | MAPT (0.55) | MEN1KMT2ANR4A2MAPTLMNA | |
| SCHEMBL27519354 | 0.87 | MAPT (0.54) | MEN1KMT2ANR4A2MAPTLMNA | |
| SCHEMBL11262742 | 0.87 | MAPT (0.54) | MEN1KMT2ANR4A2MAPTLMNA | |
| SCHEMBL16396254 | 0.87 | RAB9A (0.60) | MEN1KMT2AALDH1A1RAB9AMAOB | |
| SCHEMBL862870 | 0.83 | MEN1 (0.93) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL1426961 | 0.83 | MEN1 (1.00) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL708968 | 0.83 | GCK (0.53) | MEN1KMT2ANR4A2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337272-A | BRONCHODILATOR AGENTS | VALEAS S. R. L. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1982-06-29 | — | — | US | disclosed |
| US-4252824-A | BRONCHODILATOR AGENTS | VALEAS S.R.L., INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1981-02-24 | — | — | US | disclosed |