Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268028 | 0.82 | ACE (0.32) | ACE | |
| SCHEMBL11277867 | 0.80 | ACE (0.49) | ACE | |
| SCHEMBL20697815 | 0.78 | PIK3CD (0.35) | — | |
| SCHEMBL11262188 | 0.76 | ACE (0.55) | ACEKMT2A | |
| SCHEMBL7378968 | 0.75 | ACE (0.48) | ACE | |
| SCHEMBL11264120 | 0.75 | ACE (0.44) | ACEKMT2A | |
| SCHEMBL11264125 | 0.75 | ACE (0.44) | ACEKMT2A | |
| SCHEMBL11450137 | 0.73 | ACE (0.46) | ACE | |
| SCHEMBL11450681 | 0.73 | ACE (0.46) | ACE | |
| SCHEMBL11450135 | 0.73 | ACE (0.46) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321392-A | Mercaptoacyl derivatives of 4-oxazolidine-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1982-03-23 | — | — | US | disclosed |