Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PEPD | P12955 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697815 | 0.82 | PIK3CD (0.35) | — | |
| SCHEMBL11272471 | 0.80 | ACE (0.31) | ACEKDM4EF2RENLMNA | |
| SCHEMBL11265707 | 0.80 | ACE (0.46) | ACE | |
| SCHEMBL11272461 | 0.80 | ACE (0.31) | ACEKDM4EF2RENLMNA | |
| SCHEMBL11275389 | 0.75 | ACE (0.43) | ACE | |
| SCHEMBL11275384 | 0.75 | ACE (0.43) | ACE | |
| SCHEMBL17428585 | 0.73 | ATM (0.36) | — | |
| SCHEMBL19083693 | 0.73 | ATM (0.36) | — | |
| SCHEMBL11388204 | 0.73 | ACE (0.55) | ACEKDM4EF2RENLMNA | |
| SCHEMBL19084015 | 0.72 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321392-A | Mercaptoacyl derivatives of 4-oxazolidine-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1982-03-23 | — | — | US | disclosed |