SCHEMBL11265729

SCHEMBL11265729

CCCCCCCCCCCCCCNCCN1CCN=CCC(C)C1=O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
GBA1 P04062 1/20 0.33
OPRM1 P35372 3/20 0.31
OPRD1 P41143 3/20 0.31
OPRK1 P41145 3/20 0.31
OPRL1 P41146 3/20 0.31
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31
GNAI1 P63096 1/20 0.31
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC3 O15379 2/20 0.30
HDAC8 Q9BY41 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11265726 1.00 ALDH1A1 (0.33) ALDH1A1GBA1OPRM1OPRD1OPRK1
SCHEMBL11254432 0.85 PDCD4 (0.34) GBA1
SCHEMBL11254434 0.85 PDCD4 (0.34) GBA1
SCHEMBL11264576 0.78 BCHE (0.35) ALDH1A1TSHRKMT2A
SCHEMBL11264587 0.78 BCHE (0.35) ALDH1A1TSHRKMT2A
SCHEMBL11253058 0.76 GBA1 (0.35) ALDH1A1GBA1GNAI3GNAO1GNAI1
SCHEMBL11265723 0.75
SCHEMBL11265365 0.73 ALDH1A1 (0.36) ALDH1A1OPRM1OPRD1OPRK1OPRL1
SCHEMBL11252860 0.69 GBA1 (0.48) ALDH1A1GBA1
SCHEMBL11130692 0.68 ALDH1A1 (0.41) ALDH1A1GNAI3GNAO1GNAI1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4346087-A CORROSION RESISTANCE TOHO CHEMICAL INDUSTRY CO., LTD. (JP) 1982-08-24 US claimed
US-4346087-A CORROSION RESISTANCE TOHO CHEMICAL INDUSTRY CO., LTD. (JP) 1982-08-24 US disclosed