Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265734 | 1.00 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL8571513 | 0.79 | HMGCR (0.37) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL8571510 | 0.79 | HMGCR (0.37) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL10880649 | 0.79 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL10880652 | 0.79 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL11067787 | 0.77 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL11067789 | 0.77 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL8406762 | 0.77 | HMGCR (0.34) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL8406765 | 0.77 | HMGCR (0.34) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| Acetic Acid SCHEMBL27494445 | 0.77 | HMGCR (0.34) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003683-B1 | PROCESS FOR PREPARING HIGH CIS 3-(2,2,2-TRICHLOROETHYL)-2,2-DIMETHYLCYCLOPROPANE-1-CARBOXYLATES | FMC Corporation (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4166064-A | 4,6,6,6 -TETRACHLORO-3,3-DIMETHYLHEXANOATE, ALKALI METAL TERT-ALKOXIDE | FMC CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
| EP-0003683-A2 | Process for preparing high cis 3-(2,2,2-trichloroethyl)-2,2-dimethylcyclopropane-1-carboxylates | FMC Corporation (US) | 1979-08-22 | — | — | EP | disclosed |