Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067789 | 1.00 | TSHR (0.36) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL5683289 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL5683291 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL10957394 | 0.82 | TSHR (0.37) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL10880317 | 0.82 | TSHR (0.37) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL9796686 | 0.81 | GAA (0.40) | HSD17B10MGAMGAASIMGAM2 | |
| SCHEMBL9796681 | 0.81 | GAA (0.40) | HSD17B10MGAMGAASIMGAM2 | |
| SCHEMBL5686096 | 0.79 | — | — | |
| SCHEMBL5686092 | 0.79 | — | — | |
| SCHEMBL11265736 | 0.77 | HMGCR (0.42) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092482-A | Process for preparing 6,6,6-trihalo-3,3-dimethyl-4-hexenoates | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1978-05-30 | — | — | US | claimed |
| US-4468521-A | Method of producing gamma-halogeno-delta unsaturated carboxylic acid esters | KURARAY CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4458090-A | RECYCLING LACTONE BY-PRODUCT | KURARAY CO., LTD. (JP) | 1984-07-03 | — | — | US | disclosed |
| US-4092482-A | Process for preparing 6,6,6-trihalo-3,3-dimethyl-4-hexenoates | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1978-05-30 | — | — | US | disclosed |