Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035063 | 0.87 | HPGD (0.62) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11535079 | 0.86 | MAPT (0.73) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11537177 | 0.84 | HPGD (0.51) | HPGDKMT2AALDH1A1 | |
| SCHEMBL11299829 | 0.83 | HPGD (1.00) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11542196 | 0.82 | MAPT (0.75) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| Methane SCHEMBL3400213 | 0.81 | HPGD (0.97) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11536593 | 0.81 | SRD5A2 (0.50) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL22531009 | 0.81 | HPGD (0.62) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11532822 | 0.80 | HPGD (0.73) | HPGDKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL1943035 | 0.79 | HPGD (0.70) | HPGDKMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159986-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | ROUSSEL UCLAF (FR) | 1979-07-03 | — | — | US | claimed |
| US-4318918-A | ANTIINFLAMMATORY ANALGESICS | ROUSSEL UCLAF (FR) | 1982-03-09 | — | — | US | disclosed |
| US-4318918-A | ANTIINFLAMMATORY ANALGESICS | ROUSSEL UCLAF (FR) | 1982-03-09 | — | — | US | disclosed |
| US-4318918-A | ANTIINFLAMMATORY ANALGESICS | ROUSSEL UCLAF (FR) | 1982-03-09 | — | — | US | disclosed |
| US-4159986-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | ROUSSEL UCLAF (FR) | 1979-07-03 | — | — | US | disclosed |