Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534779 | 0.87 | KMT2A (0.65) | SRD5A2KMT2AHPGDCES2MEN1 | |
| SCHEMBL11265763 | 0.81 | HPGD (0.71) | SRD5A2KMT2AHPGDFFAR1MEN1 | |
| SCHEMBL11532430 | 0.78 | KMT2A (0.46) | SRD5A2KMT2AHPGDCES2MEN1 | |
| SCHEMBL1237189 | 0.72 | SRD5A2 (0.79) | SRD5A2KMT2AHPGDCES2MEN1 | |
| SCHEMBL11536587 | 0.72 | CYP3A4 (0.67) | SRD5A2KMT2AHPGDCES2MEN1 | |
| SCHEMBL11535931 | 0.72 | NPSR1 (0.40) | SRD5A2KMT2AHPGDCES2MEN1 | |
| SCHEMBL744906 | 0.72 | CTNNB1 (0.62) | SRD5A2KMT2ACES2FFAR1MEN1 | |
| SCHEMBL11535079 | 0.72 | MAPT (0.73) | SRD5A2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL1044812 | 0.71 | SRD5A2 (0.83) | SRD5A2CES2VNN1LMNA | |
| SCHEMBL365336 | 0.70 | FFAR1 (0.70) | KMT2AFFAR1MEN1MAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159986-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | ROUSSEL UCLAF (FR) | 1979-07-03 | — | — | US | disclosed |