Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28377838 | 0.77 | LMNA (0.52) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11741360 | 0.74 | LMNA (0.61) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| Acetic Acid SCHEMBL28371708 | 0.73 | LMNA (0.54) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11731941 | 0.72 | LMNA (0.50) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11555067 | 0.72 | — | — | |
| SCHEMBL10459087 | 0.70 | ASAH1 (0.72) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11239635 | 0.69 | LMNA (0.70) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11602434 | 0.69 | LMNA (0.56) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL10632769 | 0.68 | SMN1; SMN2 (0.46) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| Acetic Acid SCHEMBL28371629 | 0.68 | LMNA (0.58) | LMNACYP3A4CYP2D6MAPK3ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54027578-A | — | — | None | — | — | JP | disclosed |
| JP-57028066-A | — | — | None | — | — | JP | disclosed |
| JP-S5728066-A | GLYCEROL DERIVATIVE OF 5-FLUOROURACIL | SANKYO CO LTD | 1982-02-15 | — | — | JP | disclosed |
| JP-S5427578-A | 1-CARBOXYALKYLCARBAMOYL-5-FLUOROURACIL DERIVATIVES AND THEIR PREPARATION | MITSUI TOATSU CHEM INC | 1979-03-01 | — | — | JP | disclosed |