Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenmetozole SCHEMBL635495 | 0.87 | NISCH (0.65) | NISCHMAOAMAOBADRA1AADRA1D | |
| Fenmetozole SCHEMBL30295426 | 0.87 | NISCH (0.65) | NISCHMAOAMAOBADRA1AADRA1D | |
| Fenmetozole SCHEMBL635494 | 0.86 | NISCH (0.63) | NISCHMAOAMAOBADRA1AADRA1D | |
| Fenmetozole SCHEMBL29913217 | 0.86 | NISCH (0.63) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL3178323 | 0.83 | NISCH (0.60) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL11542973 | 0.82 | NISCH (0.59) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL11256269 | 0.81 | NISCH (0.58) | NISCHMAOAMAOBADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL11544075 | 0.81 | NISCH (0.58) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL8155449 | 0.81 | NISCH (0.60) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL3173356 | 0.81 | NISCH (0.60) | NISCHMAOAMAOBADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343809-A | ANTIANEMIA | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | claimed |
| US-4343809-A | ANTIANEMIA | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |