Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenmetozole SCHEMBL635495 | 1.00 | NISCH (0.65) | NISCHMAOAMAOBHTR1AADRA2A | |
| Fenmetozole SCHEMBL635494 | 0.98 | NISCH (0.63) | NISCHMAOAMAOBHTR1AADRA2A | |
| Fenmetozole SCHEMBL29913217 | 0.98 | NISCH (0.63) | NISCHMAOAMAOBHTR1AADRA2A | |
| SCHEMBL11265808 | 0.87 | NISCH (0.60) | NISCHMAOAMAOBHTR1AADRA2A | |
| SCHEMBL3178323 | 0.87 | NISCH (0.60) | NISCHMAOAMAOBHTR1AADRA2A | |
| SCHEMBL8155449 | 0.87 | NISCH (0.60) | NISCHMAOAMAOBHTR1AADRA2A | |
| SCHEMBL3173356 | 0.87 | NISCH (0.60) | NISCHMAOAMAOBHTR1AADRA2A | |
| Fenmetozole SCHEMBL11252776 | 0.83 | ADRA1A (0.48) | NISCHMAOAMAOBHTR1AADRA2A | |
| SCHEMBL3172922 | 0.83 | NISCH (0.71) | NISCHMAOAMAOBHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11251146 | 0.81 | NISCH (0.69) | NISCHMAOAMAOBHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11607458-B2 | Enrichment-triggered chemical delivery system | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11607458-B2 | Enrichment-triggered chemical delivery system | HMGB1, PAICS, CCL2 | NISCH 3953/4885MAOA 1799/4885MAOB 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.