Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21096753 | 0.82 | — | — | |
| SCHEMBL11224155 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL2101479 | 0.78 | KDM4E (0.37) | — | |
| SCHEMBL1613076 | 0.77 | — | — | |
| SCHEMBL1613074 | 0.77 | — | — | |
| SCHEMBL12714695 | 0.77 | — | — | |
| SCHEMBL15955649 | 0.75 | CYP3A4 (0.36) | — | |
| SCHEMBL19924785 | 0.75 | CYP3A4 (0.36) | — | |
| SCHEMBL2171359 | 0.75 | CYP3A4 (0.36) | — | |
| SCHEMBL17331178 | 0.75 | CYP3A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335127-A | POTENT SEROTONIN ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-06-15 | — | — | US | disclosed |
| EP-0013612-A2 | (Piperidinylalkyl)quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-07-23 | — | — | EP | disclosed |