SCHEMBL11266879

SCHEMBL11266879

CC(C)[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.46
SLC28A2 O43868 1/20 0.46
SLC29A1 Q99808 1/20 0.46
SLC28A3 Q9HAS3 1/20 0.46
P2RY14 Q15391 3/20 0.39
P2RY2 P41231 4/20 0.34
P2RY6 Q15077 6/20 0.34
P2RY4 P51582 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18660233 0.91 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL18660220 0.90 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5574929 0.89 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4064959 0.86 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL2367603 0.85 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL31146428 0.83 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL15111321 0.83 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL31694388 0.83 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4055607 0.83 SLC28A1 (0.42) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL12658269 0.82 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019765-A Specific mesothelin-targeted CAR-expressing immune cells and uses thereof 武田药品工业株式会社 2024-05-10 CN disclosed
EP-3986409-A1 URIDINE PHOSPHORYLASE (UPASE) INHIBITORS FOR TREATMENT OF LIVER CONDITIONS Tosk, Inc. (US) 2022-04-27 EP disclosed
WO-2020257400-A1 URIDINE PHOSPHORYLASE (UPASE) INHIBITORS FOR TREATMENT OF LIVER CONDITIONS TOSK, INC. (US) 2020-12-24 WO disclosed
CN-1314913-A Targeted combinatorial compound libraries and efficient assays for screening GLYCODESIGN INC (CA) 2001-09-26 CN disclosed
US-4339396-A Process for the preparation of naphthalenesulphonyl chloride BAYER AKTIENGESELLSCHAFT (DE) 1982-07-13 US disclosed