SCHEMBL4055607

SCHEMBL4055607

C=CC(N)[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.42
SLC28A2 O43868 1/20 0.42
SLC29A1 Q99808 1/20 0.42
SLC28A3 Q9HAS3 1/20 0.42
P2RY14 Q15391 4/20 0.36
P2RY6 Q15077 5/20 0.32
P2RY2 P41231 3/20 0.32
PYGB P11216 1/20 0.32
P2RY4 P51582 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL1457055 0.96 P2RY14 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL18660233 0.85 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4064959 0.83 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL11266879 0.83 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL2367603 0.80 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL18660220 0.80 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL23831167 0.79 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL7456552 0.79 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5574929 0.79 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL154357 0.79 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
US-10273484-B2 Double-stranded RNA conjugates and their use RIBOXX GMBH (DE) 2019-04-30 US claimed
US-20170107517-A1 Double-Stranded RNA Conjugates And Their Use RIBOXX GMBH (DE) 2017-04-20 US claimed
EP-3126501-A1 DOUBLE-STRANDED RNA CONJUGATES AND THEIR USE RiboxX GmbH (DE) 2017-02-08 EP claimed
WO-2015144736-A1 DOUBLE-STRANDED RNA CONJUGATES AND THEIR USE RIBOXX GMBH (DE) 2015-10-01 WO claimed
EP-1572902-B1 HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES LIFE TECHNOLOGIES CORP (US) 2014-06-11 EP claimed
US-20260043089-A1 COMPOSITIONS AND METHODS FOR DETECTING CIRCULATING TUMOR DNA QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2026-02-12 US disclosed
US-12404556-B2 Compositions and methods for detecting circulating tumor DNA QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2025-09-02 US disclosed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO disclosed
WO-2024249967-A1 RNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-12-05 WO disclosed
CN-117004721-A Compositions and methods for detecting circulating tumor DNA 奎斯特诊断投资有限责任公司 2023-11-07 CN disclosed
CN-110741096-B Compositions and methods for detecting circulating tumor DNA 奎斯特诊断投资有限责任公司 2023-07-14 CN disclosed
US-20230124718-A1 NOVEL ADAPTOR FOR NUCLEIC ACID SEQUENCING AND METHOD OF USE Roche Sequencing Solutions, Inc. 2023-04-20 US disclosed
US-7547530-B2 Nucleotide compositions comprising photocleavable markers and methods of preparation thereof AMBERGEN, INC. (US) 2009-06-16 US disclosed
EP-1415001-A4 NUCLEOTIDE COMPOSITIONS COMPRISING PHOTOCLEAVABLE MARKERS AND METHODS OF PREPARATION THEREOF AMBERGEN INC (US) 2008-02-20 EP disclosed
US-20060252923-A1 Nucleotide compositions comprising photocleavable markers and methods of preparation thereof AMBERGEN, INC. (US) 2006-11-09 US disclosed
US-7057031-B2 Nucleotide compositions comprising photocleavable markers and methods of preparation thereof AMBERGEN, INC. (US) 2006-06-06 US disclosed
EP-1415001-A2 NUCLEOTIDE COMPOSITIONS COMPRISING PHOTOCLEAVABLE MARKERS AND METHODS OF PREPARATION THEREOF Ambergen, Inc. (US) 2004-05-06 EP disclosed
US-20030099972-A1 Nucleotide compositions comprising photocleavable markers and methods of preparation thereof AMBERGEN, INC. (US) 2003-05-29 US disclosed
WO-2003006625-A2 NUCLEOTIDE COMPOSITIONS COMPRISING PHOTOCLEAVABLE MARKERS AND METHODS OF PREPARATION THEREOF AMBERGEN, INC. (US) 2003-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252923-A1 Nucleotide compositions comprising photocleavable markers and methods of preparation thereof POLN, NT5C3B, RNGTT SLC28A1 342/4885SLC28A2 341/4885SLC29A1 77/4885
US-20260043089-A1 COMPOSITIONS AND METHODS FOR DETECTING CIRCULATING TUMOR DNA DNMT3A, DNMT3L, MCTS1 SLC28A1 1141/4885SLC28A2 1194/4885SLC29A1 543/4885
US-10273484-B2 Double-stranded RNA conjugates and their use ADAR, TRDMT1, EIF2AK2 SLC28A1 1920/4885SLC28A2 1812/4885SLC29A1 1007/4885
US-20030099972-A1 Nucleotide compositions comprising photocleavable markers and methods of preparation thereof POLN, NT5C3B, RNGTT SLC28A1 342/4885SLC28A2 341/4885SLC29A1 77/4885
US-20170107517-A1 Double-Stranded RNA Conjugates And Their Use ADAR, TRDMT1, EIF2AK2 SLC28A1 1920/4885SLC28A2 1812/4885SLC29A1 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.