SCHEMBL11266934

SCHEMBL11266934

C=C(C#N)C(=O)OCCOCCCCC

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.56
ALDH1A1 P00352 1/20 0.56
THRB P10828 2/20 0.42
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
MAPT P10636 1/20 0.42
CES2 O00748 2/20 0.40
NAAA Q02083 1/20 0.37
DGKA P23743 1/20 0.37
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
EPHX1 P07099 1/20 0.35
CYP3A4 P08684 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11252800 0.98 TSHR (0.54) TSHRALDH1A1THRBMEN1HTT
SCHEMBL16174654 0.98 TSHR (0.54) TSHRALDH1A1THRBMEN1HTT
SCHEMBL21932828 0.98 TSHR (0.54) TSHRALDH1A1THRBMEN1HTT
SCHEMBL28709225 0.95 TSHR (0.58) TSHRALDH1A1THRBMEN1HTT
SCHEMBL21932807 0.95 TSHR (0.58) TSHRALDH1A1THRBMEN1HTT
SCHEMBL35575 0.95 TSHR (0.58) TSHRALDH1A1THRBMEN1HTT
SCHEMBL4892534 0.92 TSHR (0.58) TSHRALDH1A1THRBMEN1HTT
Acetic Acid SCHEMBL27835388 0.91 TSHR (0.53) TSHRALDH1A1THRBMEN1HTT
SCHEMBL618797 0.90 TSHR (0.63) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL4888255 0.89 TSHR (0.58) TSHRALDH1A1THRBZDHHC20MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9657205-B2 Adhesive beads Dry, Carolyn (US) 2017-05-23 US claimed
US-20150361314-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2015-12-17 US claimed
EP-2951256-A1 ADHESIVE BEADS Dry, Carolyn M. (US) 2015-12-09 EP claimed
WO-2014121223-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2014-08-07 WO claimed
US-4321180-A COMPRISING AN ALKYLOXYALKYL 2-CYANOACRYLATE, MOISTURE AND A POLYMERIZATION INHIBITOR TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1982-03-23 US claimed
US-10011149-B2 Self-repairing inflatable articles DRY CAROLYN M (US) 2018-07-03 US disclosed
US-9694629-B1 Self-repairing inflatable articles incorporating an integrated self-repair system Dry, Carolyn (US) 2017-07-04 US disclosed
US-9683816-B2 Self-repairing armor Dry, Carolyn (US) 2017-06-20 US disclosed
US-9657205-B2 Adhesive beads Dry, Carolyn (US) 2017-05-23 US disclosed
US-20160195367-A1 SELF-REPAIRING ARMOR DRY CAROLYN (US) 2016-07-07 US disclosed
US-20150361314-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2015-12-17 US disclosed
EP-2951256-A1 ADHESIVE BEADS Dry, Carolyn M. (US) 2015-12-09 EP disclosed
US-20150056391-A1 SELF-REPAIRING INFLATABLE ARTICLES DRY CAROLYN M (US) 2015-02-26 US disclosed
US-8877309-B1 Self-repairing inflatable articles DRY CAROLYN M (US) 2014-11-04 US disclosed
WO-2014121223-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2014-08-07 WO disclosed
US-4321180-A COMPRISING AN ALKYLOXYALKYL 2-CYANOACRYLATE, MOISTURE AND A POLYMERIZATION INHIBITOR TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1982-03-23 US disclosed