SCHEMBL4892534

SCHEMBL4892534

C=C(C#N)C(=O)OCCCCOCCCC

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.40
ATM Q13315 1/20 0.39
NAAA Q02083 1/20 0.38
CES2 O00748 1/20 0.37
RAD52 P43351 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
THRB P10828 2/20 0.36
EPHX1 P07099 1/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
TP53 P04637 1/20 0.35
ACHE P22303 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4888255 0.97 TSHR (0.58) TSHRALDH1A1HPGDZDHHC20ATM
SCHEMBL35575 0.93 TSHR (0.58) TSHRALDH1A1HPGDZDHHC20ATM
SCHEMBL28709225 0.93 TSHR (0.58) TSHRALDH1A1HPGDZDHHC20ATM
SCHEMBL21932807 0.93 TSHR (0.58) TSHRALDH1A1HPGDZDHHC20ATM
Enbucrilate SCHEMBL24796 0.93 TSHR (0.66) TSHRALDH1A1HPGDATMNAAA
SCHEMBL11266934 0.92 TSHR (0.56) TSHRALDH1A1ZDHHC20NAAACES2
Enbucrilate SCHEMBL6465405 0.92 TSHR (0.61) TSHRALDH1A1HPGDATMNAAA
Ocrylate SCHEMBL19579379 0.92 TSHR (0.61) TSHRALDH1A1HPGDATMNAAA
Enbucrilate SCHEMBL29026258 0.92 TSHR (0.61) TSHRALDH1A1HPGDATMNAAA
SCHEMBL618797 0.91 TSHR (0.63) TSHRALDH1A1HPGDATMNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11629262-B2 Liquid composition set, cured product forming method, and liquid composition RICOH COMPANY, LTD. (JP) 2023-04-18 US disclosed
CN-113874459-A Flexible photocurable cyanoacrylate compositions 汉高知识产权控股有限责任公司 2021-12-31 CN disclosed
US-20210102081-A1 LIQUID COMPOSITION SET, CURED PRODUCT FORMING METHOD, AND LIQUID COMPOSITION RICOH COMPANY, LTD. (JP) 2021-04-08 US disclosed
CN-105246872-A Cyanoacrylate compositions Henkel US IP LLC 2016-01-13 CN disclosed
US-20080293872-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-27 US disclosed
US-20080287574-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-20 US disclosed