Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954146 | 0.85 | KMT2A (0.76) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL196599 | 0.82 | KMT2A (1.00) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL8315301 | 0.82 | KMT2A (1.00) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL954303 | 0.81 | KMT2A (0.73) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL2937795 | 0.81 | KMT2A (0.73) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL11253412 | 0.80 | CYP1A2 (0.65) | KMT2AALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL18766608 | 0.80 | EPHB3 (0.58) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL2829842 | 0.79 | MAPK1 (1.00) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL24655998 | 0.78 | MAPK1 (0.74) | KMT2AMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL19675464 | 0.78 | KMT2A (0.69) | KMT2AMAPK1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352804-A | ANTIULCER AGENTS, GASTROINTESTINAL DISORDERS | ACF CHEMIEFARMA NV (NL) | 1982-10-05 | — | — | US | disclosed |