Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.88 |
| ▸ | DRD3 | P35462 | 6/20 | 0.88 |
| ▸ | DRD4 | P21917 | 5/20 | 0.88 |
| ▸ | HTR1A | P08908 | 4/20 | 0.88 |
| ▸ | MEN1 | O00255 | 2/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.88 |
| ▸ | HTR5A | P47898 | 2/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.88 |
| ▸ | TSHR | P16473 | 1/20 | 0.88 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267208 | 1.00 | DRD2 (0.88) | DRD2DRD3DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9307503 | 0.99 | DRD2 (0.86) | DRD2DRD3DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9307498 | 0.99 | DRD2 (0.86) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL29766823 | 0.94 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL29389256 | 0.94 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL273985 | 0.94 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9306802 | 0.93 | DRD2 (0.97) | DRD2DRD3DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9358749 | 0.93 | DRD2 (0.97) | DRD2DRD3DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9309640 | 0.93 | DRD2 (0.97) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL9559065 | 0.86 | DRD2 (0.84) | DRD2DRD3DRD4HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064964-A1 | Therapeutically useful 1-alkyl-2-aminotetralin derivatives | Astra Läkemedel Aktiebolag (SE) | 1982-11-17 | — | — | EP | disclosed |