SCHEMBL11267293

SCHEMBL11267293

CCOC(=O)CCC(C)=CCCC(CBr)OC(C)OC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
NR1I2 O75469 1/20 0.31
PGR P06401 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
PTGS2 P35354 1/20 0.31
PDE4D Q08499 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11276910 0.88 TSHR (0.35)
SCHEMBL11268420 0.88 PPARG (0.31) PPARGPPARDPPARA
SCHEMBL11281561 0.88 CYP2D6 (0.33) CYP2D6CYP2C19PPARGPPARDPPARA
SCHEMBL11271340 0.78 TSHR (0.31)
SCHEMBL11279331 0.76 PPARG (0.31) PPARGPPARDPPARA
SCHEMBL11268922 0.75 TSHR (0.35) ALDH1A1
SCHEMBL11277698 0.75 MAPT (0.33) PPARGPPARDPPARA
SCHEMBL11268424 0.73 PPARG (0.33) PPARGPPARDPPARA
SCHEMBL29265365 0.71 ALDH1A1 (0.48) TRPA1ALDH1A1NR1I2PGRADORA3
SCHEMBL22828529 0.69 CYP1A2 (0.53) CYP2D6CYP2C19TRPA1ALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0054909-A2 9-Halo-8-hydroxy-4-methyl-4-nonenoic acids, derivatives thereof and a process for their preparation MITSUBISHI KASEI CORPORATION (JP) 1982-06-30 EP disclosed