Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GRM6 | O15303 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048871 | 0.77 | NPSR1 (0.43) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL2917128 | 0.73 | MAPK1 (0.39) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL12763454 | 0.72 | APLNR (0.40) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL28493026 | 0.72 | MAPK1 (0.52) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL4408319 | 0.71 | MAPK1 (0.38) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL25330082 | 0.71 | — | — | |
| SCHEMBL19557132 | 0.71 | — | — | |
| SCHEMBL5314714 | 0.71 | — | — | |
| SCHEMBL17479965 | 0.71 | — | — | |
| SCHEMBL459480 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349565-A | Cyclobutanedicarboxisoimides and use thereof as fungicides | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |