Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847192 | 0.76 | MAP2K1 (0.40) | TRPA1TSHR | |
| SCHEMBL2863135 | 0.74 | ALDH1A1 (0.46) | TRPA1TSHR | |
| SCHEMBL11453434 | 0.74 | ESR1 (0.45) | TSHR | |
| SCHEMBL7868609 | 0.74 | IDO1 (0.40) | TRPA1 | |
| SCHEMBL2245671 | 0.74 | ALDH1A1 (0.46) | TRPA1TSHR | |
| SCHEMBL953060 | 0.74 | TSHR (0.33) | TRPA1TSHR | |
| SCHEMBL7865917 | 0.74 | IDO1 (0.40) | TRPA1TSHRTAAR1 | |
| SCHEMBL4088437 | 0.73 | TAAR1 (0.33) | TAAR1 | |
| Water SCHEMBL11017550 | 0.73 | CYP2D6 (0.43) | TSHRTAAR1 | |
| Hydrochloric Acid SCHEMBL3816918 | 0.72 | ESR1 (0.43) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360511-A | Amines useful as brain imaging agents | MEDI-PHYSICS, INC. (US) | 1982-11-23 | — | — | US | disclosed |
| EP-0011858-A1 | Radioiodine containing amines, their preparation and their use as brain imaging agents | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-06-11 | — | — | EP | disclosed |