Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262921 | 1.00 | ACE (0.78) | ACELMNASMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL10981416 | 0.90 | ACE (0.64) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7333220 | 0.90 | ACE (0.79) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11262743 | 0.89 | ACE (0.77) | ACELMNASMN1; SMN2 | |
| SCHEMBL11267471 | 0.89 | ACE (0.77) | ACELMNASMN1; SMN2 | |
| SCHEMBL683537 | 0.88 | ACE (0.81) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7266938 | 0.88 | ACE (0.81) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11259353 | 0.88 | ACE (0.68) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11292868 | 0.88 | ACE (0.69) | ACELMNASMN1; SMN2MEN1KMT2A | |
| Enalapril SCHEMBL8089096 | 0.87 | ACE (1.00) | ACELMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049506-A1 | N-carboxyalkyl dipeptides, a process for preparing and a pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-04-14 | — | — | EP | claimed |