Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262743 | 1.00 | ACE (0.77) | ACELMNASMN1; SMN2LTA4HREN | |
| SCHEMBL11263522 | 0.92 | ACE (0.77) | ACELMNASMN1; SMN2LTA4H | |
| SCHEMBL11255114 | 0.91 | ACE (0.65) | ACELMNASMN1; SMN2LTA4HREN | |
| SCHEMBL11199445 | 0.90 | ACE (0.87) | ACELMNASMN1; SMN2 | |
| SCHEMBL11204194 | 0.90 | ACE (0.87) | ACELMNASMN1; SMN2 | |
| SCHEMBL24506200 | 0.90 | ACE (0.77) | ACELMNASMN1; SMN2 | |
| SCHEMBL7324352 | 0.89 | ACE (0.77) | ACELMNASMN1; SMN2LTA4H | |
| SCHEMBL7321061 | 0.89 | ACE (0.77) | ACELMNASMN1; SMN2LTA4H | |
| SCHEMBL11267866 | 0.89 | ACE (0.78) | ACELMNASMN1; SMN2 | |
| SCHEMBL11262921 | 0.89 | ACE (0.78) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049506-A1 | N-carboxyalkyl dipeptides, a process for preparing and a pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-04-14 | — | — | EP | claimed |