Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47974 | 0.81 | IDO1 (0.58) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL4261946 | 0.71 | CYP1A2 (0.57) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL6943180 | 0.70 | IDO1 (0.40) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL4773313 | 0.68 | IDO1 (0.50) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL3635722 | 0.68 | CYP1A2 (0.64) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL5540931 | 0.68 | TDP1 (0.46) | HTTL3MBTL1GAA | |
| SCHEMBL5540927 | 0.68 | TDP1 (0.46) | HTTL3MBTL1GAA | |
| SCHEMBL155790 | 0.68 | IDO1 (0.60) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL1047227 | 0.68 | IDO1 (0.60) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL11621292 | 0.67 | IDO1 (0.65) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052028-A1 | Hexapeptides, their manufacture, their use in medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1982-05-19 | — | — | EP | disclosed |