Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.43 |
| ▸ | USP2 | O75604 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPY2R | P49146 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271869 | 0.90 | IDO1 (0.44) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL11260380 | 0.86 | CYP3A4 (0.48) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL11262282 | 0.85 | USP2 (0.44) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL11267974 | 0.85 | CYP3A4 (0.42) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL11268613 | 0.84 | OGG1 (0.43) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL11277351 | 0.83 | CYP3A4 (0.45) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL10879985 | 0.83 | HSP90AA1 (0.44) | CYP3A4TDP1USP2LMNAMAPT | |
| Nitric Acid SCHEMBL11267999 | 0.82 | CYP3A4 (0.50) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL11346991 | 0.82 | OGG1 (0.45) | IDO1CYP3A4TDP1USP2LMNA | |
| SCHEMBL11260241 | 0.81 | CYP3A4 (0.40) | IDO1CYP3A4TDP1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358458-A | BACTERICIDE, FUNGICIDES | NORDMARK-WERKE GMBH (DE) | 1982-11-09 | — | — | US | disclosed |