Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272382 | 0.78 | — | — | |
| SCHEMBL11449481 | 0.78 | — | — | |
| SCHEMBL11261713 | 0.76 | CRBN (0.36) | ALDH1A1LMNACRBN | |
| SCHEMBL11269135 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL11269132 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL11262448 | 0.72 | ALOX5 (0.39) | CRBN | |
| SCHEMBL11267205 | 0.72 | MAPT (0.43) | ALDH1A1LMNA | |
| SCHEMBL11257799 | 0.71 | KMT2A (0.38) | ALDH1A1LMNACRBN | |
| SCHEMBL11274787 | 0.71 | CRBN (0.39) | ALDH1A1LMNACRBN | |
| SCHEMBL11269817 | 0.71 | CRBN (0.39) | ALDH1A1LMNACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |