Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14241832 | 0.82 | HIF1A (0.57) | HTTMTNR1AALDH1A1 | |
| SCHEMBL4183114 | 0.80 | EPHX2 (0.80) | EPHX2HSD17B10TRPV1MEN1MAPT | |
| SCHEMBL30445464 | 0.80 | EPHX2 (0.80) | EPHX2HSD17B10TRPV1MEN1MAPT | |
| SCHEMBL19043177 | 0.80 | EPHX2 (0.80) | EPHX2HSD17B10TRPV1MEN1MAPT | |
| SCHEMBL27029534 | 0.80 | EPHX2 (0.80) | EPHX2HSD17B10TRPV1MEN1MAPT | |
| SCHEMBL1456740 | 0.80 | EPHX2 (0.80) | EPHX2HSD17B10TRPV1MEN1MAPT | |
| SCHEMBL3810079 | 0.80 | MTNR1A (0.69) | MTNR1ATRPV1MEN1KMT2A | |
| SCHEMBL27680999 | 0.79 | HIF1A (0.60) | ALDH1A1TRPV1 | |
| SCHEMBL7426779 | 0.78 | EPHX2 (0.78) | EPHX2HSD17B10TRPV1 | |
| SCHEMBL225174 | 0.77 | EPHX2 (0.73) | HTTEPHX2TRPV1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |