Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGAV | P06756 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.31 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL4798781 | 0.76 | NAPRT (0.53) | TSHRNAPRTTDP1TP53CYP3A4 | |
| Pyridine SCHEMBL10977701 | 0.75 | NAPRT (0.60) | TSHRNAPRTTDP1TP53CYP3A4 | |
| Pyridine SCHEMBL179840 | 0.75 | NAPRT (0.60) | TSHRNAPRTTDP1TP53CYP3A4 | |
| Pyridine SCHEMBL11125163 | 0.75 | NAPRT (0.60) | TSHRNAPRTTDP1TP53CYP3A4 | |
| Pyridine SCHEMBL3467693 | 0.75 | NAPRT (0.60) | TSHRNAPRTTDP1TP53CYP3A4 | |
| Pyridine SCHEMBL265932 | 0.75 | — | — | |
| Pyridine SCHEMBL28013164 | 0.75 | NAPRT (0.69) | TSHRNAPRTTDP1ALDH1A1MEN1 | |
| Pyridine SCHEMBL10974779 | 0.75 | NAPRT (0.45) | TSHRNAPRTTDP1TP53CYP3A4 | |
| Pyridine SCHEMBL28185891 | 0.75 | NAPRT (0.45) | TSHRNAPRTTDP1TP53CYP3A4 | |
| Pyridine SCHEMBL27642192 | 0.74 | NAPRT (0.50) | TSHRNAPRTTDP1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321379-A | NEUROLEPTIC AGENTS AND ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1982-03-23 | — | — | US | disclosed |