Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL11125163 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL10977701 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL5844202 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL5844201 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL4558243 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL8582033 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL9246176 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL10380397 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL153596 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK | |
| Pyridine SCHEMBL11225938 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1809 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260071024-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER INC (US) | 2026-03-12 | — | — | US | claimed |
| US-20250171409-A1 | PROCESS OF PREPARATION OF INDOXACARB AND ITS INTERMEDIATES | ADAMA MAKHTESHIM LTD. (IL) | 2025-05-29 | — | — | US | claimed |
| CN-118833832-B | Oil-ice semi-solid phase coprecipitation process for synthesizing Prussian blue type positive electrode material | 哈尔滨工业大学 | 2025-02-07 | — | — | CN | claimed |
| CN-119192566-A | Non-isocyanate polyurea and preparation method thereof, water-based non-isocyanate polyurea and preparation method thereof, and anti-corrosion coating, waterproof coating and fireproof coating containing water-based non-isocyanate polyurea and preparation method thereof | 山西省建筑科学研究院集团有限公司 | 2024-12-27 | — | — | CN | claimed |
| US-12173342-B2 | Method for producing monophosphoryl lipid A | EUBIOLOGICS CO., LTD. (KR) | 2024-12-24 | — | — | US | claimed |
| CN-119080615-A | Method for preparing long-chain dibasic acid or dibasic ester | 中国科学院大连化学物理研究所 | 2024-12-06 | — | — | CN | claimed |
| US-20240393290-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2024-11-28 | — | — | US | claimed |
| CN-119019307-A | Vitamin D3Is prepared by the preparation method of (2) | 厦门金达威维生素有限公司 | 2024-11-26 | — | — | CN | claimed |
| EP-4460499-A1 | PROCESS OF PREPARATION OF INDOXACARB AND ITS INTERMEDIATES | ADAMA MAKHTESHIM LTD. (IL) | 2024-11-13 | — | — | EP | claimed |
| CN-118833832-A | Oil-ice semi-solid phase coprecipitation process for synthesizing Prussian blue type positive electrode material | 哈尔滨工业大学 | 2024-10-25 | — | — | CN | claimed |
| US-4935558-A | Reductive dechlorination of 1,1,1,2-tetrafluoro-2-chloroethane | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-06-19 | — | — | US | claimed |
| WO-1990000394-A1 | NATRIURETIC HORMONE | LOMA LINDA UNIVERSITY (US) | 1990-01-25 | — | — | WO | claimed |
| EP-0129877-B1 | NOVEL ANTIBIOTIC SF-2288 AND ITS PREPARATION METHOD | MEIJI SEIKA KAISHA LTD. (JP) | 1989-05-31 | — | — | EP | claimed |
| US-4742161-A | RED DYES | SANDOZ LTD. (CH) | 1988-05-03 | — | — | US | claimed |
| US-4722842-A | Growth inhibitory factor | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1988-02-02 | — | — | US | claimed |
| US-4333884-A | Production of acetic anhydride | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | claimed |
| US-4319038-A | BY REACTING METHYL ACETATE OR DIMETHYL ETHER WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A CATALYST SYSTEM WHICH INCLUDES AN ALIPHATIC CARBOXYLIC ACID, A MANGANESE OR RHEMIUM COMPOUND, AND A HETEROCYCLIC NITROGEN-CONTAINING SALT | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | claimed |
| US-4146603-A | TUMOR SPECIFIC GLYCOPROTEINS AND METHOD FOR DETECTING TUMORIGENIC CANCERS | RESEARCH CORPORATION (US) | 1979-03-27 | — | — | US | claimed |
| US-4085127-A | Method for producing aldehyde acids by selective ozonization of cyclo-olefins | SNIA Viscosa Societa' Nazionale Industria Application Viscosa S.p.A. (IT) | 1978-04-18 | — | — | US | claimed |
| US-4054557-A | ISOLATION FROM MAMMALIAN BLOOD | AB KABI (SW) | 1977-10-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071024-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOTUM, ALKBH3, EBP | NAPRT 3300/4885TSHR 3633/4885TDP1 2521/4885 |
| US-20250171409-A1 | PROCESS OF PREPARATION OF INDOXACARB AND ITS INTERMEDIATES | DDT, IDO2, INSR | NAPRT 1206/4885TSHR 407/4885TDP1 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.