Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265418 | 0.96 | MEN1 (0.54) | MEN1KMT2AATMQPCTALDH1A1 | |
| SCHEMBL11289197 | 0.93 | MEN1 (0.48) | MEN1KMT2AATMQPCTALDH1A1 | |
| SCHEMBL11261162 | 0.89 | MEN1 (0.50) | MEN1KMT2AATMQPCTALDH1A1 | |
| SCHEMBL11251892 | 0.88 | QPCT (0.47) | QPCTALDH1A1TSHRLMNACYP19A1 | |
| SCHEMBL11255616 | 0.86 | CYP19A1 (0.46) | MEN1KMT2AATMQPCTALDH1A1 | |
| SCHEMBL11265708 | 0.85 | CYP2A6 (0.48) | QPCTALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL11253718 | 0.85 | QPCT (0.46) | QPCTMAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11267575 | 0.85 | CYP19A1 (0.46) | CYP19A1 | |
| SCHEMBL11268918 | 0.84 | MEN1 (0.49) | MEN1KMT2AATMQPCTALDH1A1 | |
| SCHEMBL11269437 | 0.83 | QPCT (0.49) | QPCTALDH1A1TSHRLMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |