Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261162 | 0.95 | MEN1 (0.50) | MEN1KMT2AATMQPCTCYP19A1 | |
| SCHEMBL11268189 | 0.93 | MEN1 (0.52) | MEN1KMT2AATMQPCTCYP19A1 | |
| SCHEMBL11265418 | 0.89 | MEN1 (0.54) | MEN1KMT2AATMQPCTCYP19A1 | |
| SCHEMBL11255616 | 0.88 | CYP19A1 (0.46) | MEN1KMT2AATMQPCTCYP19A1 | |
| SCHEMBL11258631 | 0.87 | CYP11B1 (0.49) | QPCTCYP19A1ALDH1A1CYP11B1LMNA | |
| SCHEMBL11266898 | 0.85 | CYP3A4 (0.49) | MEN1KMT2AATMQPCTCYP19A1 | |
| SCHEMBL11254617 | 0.85 | CYP19A1 (0.40) | KMT2ACYP19A1TBXAS1 | |
| SCHEMBL11258234 | 0.85 | MEN1 (0.45) | MEN1KMT2AATMQPCTCYP19A1 | |
| SCHEMBL11253258 | 0.85 | CYP2A6 (0.50) | QPCTCYP19A1TSHRTP53ALDH1A1 | |
| SCHEMBL11269020 | 0.85 | HMOX1 (0.50) | CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |