SCHEMBL11268425

SCHEMBL11268425

CCCCC1CSC(CCc2ccc(Cl)cc2)(Cn2ccnc2)S1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HMOX1 P09601 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11267725 0.95 HMOX1 (0.46) HMOX1
SCHEMBL11266438 0.92 HMOX1 (0.40) HMOX1
SCHEMBL11267807 0.91 HMOX1 (0.44) HMOX1
SCHEMBL11265934 0.91 CYP19A1 (0.40) HMOX1
SCHEMBL11255210 0.91 HMOX1 (0.48) HMOX1
SCHEMBL11256354 0.90 HMOX1 (0.38) HMOX1
SCHEMBL11256712 0.90 HMOX1 (0.42) HMOX1
SCHEMBL11259587 0.90 HMOX1 (0.53) HMOX1
SCHEMBL11252503 0.89 CYP3A4 (0.41)
SCHEMBL11253955 0.87 HMOX1 (0.37) HMOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359475-A SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS SYNTEX (U.S.A.) INC. (US) 1982-11-16 US disclosed