Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30563091 | 1.00 | TDP1 (0.72) | TDP1TSHRSMN1; SMN2HSD17B10GPR35 | |
| SCHEMBL472112 | 0.84 | TDP1 (1.00) | TDP1TSHRSMN1; SMN2HSD17B10GPR35 | |
| SCHEMBL1424697 | 0.81 | TDP1 (0.56) | TDP1TSHRSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL29788829 | 0.81 | TDP1 (0.56) | TDP1TSHRSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL4057047 | 0.79 | MAPK1 (0.54) | TDP1TSHRSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL29355089 | 0.78 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2HSD17B10GPR35 | |
| SCHEMBL29538967 | 0.78 | TSHR (1.00) | TDP1TSHRSMN1; SMN2HSD17B10GPR35 | |
| SCHEMBL307855 | 0.78 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2HSD17B10GPR35 | |
| SCHEMBL9550119 | 0.78 | TDP1 (0.78) | TDP1TSHRSMN1; SMN2HSD17B10GPR35 | |
| SCHEMBL700469 | 0.78 | TSHR (1.00) | TDP1TSHRSMN1; SMN2HSD17B10GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260037-A | Preparation method of 2-methyl-3-nitrobenzyl ether | 西安拓超生物科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-111995577-A | Synthetic method of 4-fluoro indazole 3-carbonitrile or derivatives thereof | 上海代为化学科技有限公司 | 2020-11-27 | — | — | CN | claimed |
| CN-106854172-B | A kind of preparation method of the fluoro- 1H- indoles -4- methyl formate of 6- | 山东轩德医药科技有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-103420892-A | Preparation method of 4-fluoroindole | ASCEPION PHARMACEUTICALS INC | 2013-12-04 | — | — | CN | claimed |
| EP-1493061-A4 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE INC (US) | 2009-01-07 | — | — | EP | claimed |
| US-7132219-B2 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE INC. (US) | 2006-11-07 | — | — | US | claimed |
| EP-1493061-A2 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | Brewer Science, Inc. (US) | 2005-01-05 | — | — | EP | claimed |
| US-20030219541-A1 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE, INC. | 2003-11-27 | — | — | US | claimed |
| WO-2003087233-A2 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE, INC. (US) | 2003-10-23 | — | — | WO | claimed |
| CN-121198652-A | Water washing device for 2-fluoro-6-nitrotoluene production | 江苏永创医药科技股份有限公司 | 2025-12-26 | — | — | CN | disclosed |
| CN-121198652-A | Water washing device for 2-fluoro-6-nitrotoluene production | 江苏永创医药科技股份有限公司 | 2025-12-26 | — | — | CN | disclosed |
| EP-3958865-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2025-12-10 | — | — | EP | disclosed |
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2025-09-02 | — | — | US | disclosed |
| US-12378202-B2 | Tetrahydrobenzoazepinones and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| EP-0027214-A1 | Imidazodiazepine derivatives, process and intermediates for their preparation, medicaments containing them and their therapeutic application | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-22 | — | — | EP | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-3932407-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTICOAGULANTS | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | EGFR, ERBB2, ERBB4 | TDP1 1060/4885TSHR 2270/4885SMN1; SMN2 1682/4885 |
| US-12378202-B2 | Tetrahydrobenzoazepinones and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD2, TEAD4 | TDP1 2257/4885TSHR 2736/4885SMN1; SMN2 3403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.