Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232750 | 0.92 | MEN1 (0.56) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL11279319 | 0.88 | MEN1 (0.53) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL11271901 | 0.86 | MEN1 (0.57) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL11266275 | 0.86 | MEN1 (0.51) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL6865758 | 0.85 | MEN1 (0.62) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL29213956 | 0.84 | MEN1 (0.62) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL11264251 | 0.84 | MEN1 (0.52) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL11175152 | 0.83 | MEN1 (0.54) | MEN1KMT2AMAPTSMYD3HDAC1 | |
| SCHEMBL31215063 | 0.83 | THRB (0.55) | MEN1KMT2AMAPTSMYD3HTT | |
| SCHEMBL31215064 | 0.83 | THRB (0.55) | MEN1KMT2AMAPTSMYD3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319916-A | 3-Acyl-5-phenyl-4(1H)-pyridinones and their use as herbicides | ELI LILLY AND COMPANY (US) | 1982-03-16 | — | — | US | disclosed |