Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.56 |
| ▸ | LTA4H | P09960 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383518 | 1.00 | ACE (0.62) | ACEACE2LTA4HLMNA | |
| SCHEMBL10656412 | 0.96 | ACE (0.58) | ACEACE2LTA4HLMNA | |
| SCHEMBL33721990 | 0.95 | ACE (0.64) | ACEACE2 | |
| SCHEMBL10626642 | 0.94 | ACE (0.56) | ACEACE2LTA4H | |
| SCHEMBL31618961 | 0.93 | ACE (0.53) | ACEACE2LTA4H | |
| SCHEMBL30357026 | 0.92 | OPRK1 (0.63) | ACEACE2LMNA | |
| SCHEMBL29839269 | 0.92 | SLC6A2 (0.55) | ACE | |
| SCHEMBL29666711 | 0.91 | ACE (0.59) | ACEACE2 | |
| SCHEMBL29412259 | 0.90 | CALCRL (0.60) | ACEACE2 | |
| SCHEMBL31632671 | 0.89 | ACE (0.60) | ACEACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329473-A | HYPOTENSIVE AGENTS | SRI INTERNATIONAL | 1982-05-11 | — | — | US | disclosed |