SCHEMBL11268753

SCHEMBL11268753

C/C(=C\CC(N)C(=O)O)CC(N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 19/20 0.52
GRIK2 Q13002 13/20 0.52
SLC7A5 Q01650 1/20 0.45
GRIA4 P48058 3/20 0.44
GRIK3 Q13003 3/20 0.44
GRIK5 Q16478 3/20 0.44
GRIA2 P42262 2/20 0.44
GRIA1 P42261 1/20 0.44
GRM1 Q13255 1/20 0.42
GRM2 Q14416 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585579 0.83 GRIK1 (0.48) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL10585583 0.83 GRIK1 (0.48) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL1512922 0.80 GRIK1 (0.59) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL4854891 0.80 GRIK1 (0.68) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL1512923 0.80 GRIK1 (0.59) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL25660458 0.80 GRIK1 (0.59) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL12064021 0.80 GRIK1 (0.68) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL29950721 0.80 GRIK1 (0.68) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL26792990 0.78 GRIK1 (0.52) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL6027700 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0019112-B1 PROCESS FOR THE PREPARATION OF CYCLIC ACETALS OF TRANS-4-CHLORO-3-METHYL-2-BUTEN-1-AL AND PREPARATION OF TRANS-3-METHYL-2-BUTEN-1,4-DIAL-MONOACETALS BASF Aktiengesellschaft (DE) 1982-11-17 EP disclosed