SCHEMBL25660458

SCHEMBL25660458

C/C=C(/C)CC(N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 15/20 0.59
GRIK2 Q13002 10/20 0.59
SLC7A5 Q01650 1/20 0.50
GRIA4 P48058 3/20 0.48
GRIK3 Q13003 3/20 0.48
GRIK5 Q16478 3/20 0.48
GRIA2 P42262 2/20 0.48
GRIA1 P42261 1/20 0.48
GRM1 Q13255 1/20 0.46
GRM2 Q14416 1/20 0.46
SLC1A3 P43003 3/20 0.45
SLC1A2 P43004 3/20 0.45
SLC1A1 P43005 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1512923 1.00 GRIK1 (0.59) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL1512922 1.00 GRIK1 (0.59) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL26792990 0.84 GRIK1 (0.52) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL10585583 0.80 GRIK1 (0.48) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL11268753 0.80 GRIK1 (0.52) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL10585579 0.80 GRIK1 (0.48) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL20735515 0.78 GRIK1 (0.61) GRIK1GRIK2SLC7A5GRIA4GRIK3
SCHEMBL15624504 0.77 GRIK1 (0.58) GRIK1GRIK2GRIA4GRIK3GRIK5
SCHEMBL6028073 0.77
SCHEMBL8244 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP GRIK1 2914/4885GRIK2 3197/4885SLC7A5 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.