Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268812 | 1.00 | MAPT (0.58) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL11268810 | 1.00 | MAPT (0.58) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL11272162 | 0.92 | MAPT (0.64) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL11272165 | 0.92 | MAPT (0.64) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL11271609 | 0.80 | MAPT (0.68) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL11271604 | 0.80 | MAPT (0.68) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL11298296 | 0.76 | MAPT (0.71) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL8035724 | 0.76 | MAPT (0.71) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL21829067 | 0.75 | MAPT (0.71) | MAPTAHRCYP19A1ALDH1A1LMNA | |
| SCHEMBL10991626 | 0.72 | ADRA2C (0.46) | MAPTAHRCYP19A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |