Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.37 |
| ▸ | GLRB | P48167 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331015 | 0.88 | NPSR1 (0.42) | NPSR1GLRA3GLRBNR1H4VCAM1 | |
| SCHEMBL30763877 | 0.88 | NPSR1 (0.42) | NPSR1GLRA3GLRBNR1H4VCAM1 | |
| SCHEMBL10920960 | 0.86 | NPSR1 (0.41) | NPSR1GLRA3GLRBNR1H4VCAM1 | |
| SCHEMBL8343880 | 0.85 | VCAM1 (0.38) | NPSR1GLRA3GLRBNR1H4VCAM1 | |
| SCHEMBL251685 | 0.83 | NPSR1 (0.39) | NPSR1NR1H4VCAM1GAAKMT2A | |
| SCHEMBL11366464 | 0.83 | NPSR1 (0.39) | NPSR1NR1H4VCAM1GAAKMT2A | |
| SCHEMBL817511 | 0.83 | NPSR1 (0.39) | NPSR1NR1H4VCAM1GAAKMT2A | |
| SCHEMBL3753858 | 0.80 | NPSR1 (0.36) | NPSR1GLRA3GLRBNR1H4VCAM1 | |
| SCHEMBL29354203 | 0.79 | NPSR1 (0.43) | NPSR1GLRA3GLRBNR1H4VCAM1 | |
| SCHEMBL1823502 | 0.79 | GLRA3 (0.42) | NPSR1GLRA3GLRBVCAM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017614-B1 | PROCESS FOR THE PREPARATION OF ESTERS OF MERCAPTOALCANOLS WITH HYDROXYPHENYLCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1982-08-25 | — | — | EP | claimed |