Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.61 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pronetalol SCHEMBL31108442 | 0.83 | TSHR (1.00) | TSHRCYP1A2MEN1KMT2AHIF1A | |
| Pronetalol SCHEMBL9666931 | 0.83 | TSHR (1.00) | TSHRCYP1A2MEN1KMT2AHIF1A | |
| Pronetalol SCHEMBL78996 | 0.83 | TSHR (1.00) | TSHRCYP1A2MEN1KMT2AHIF1A | |
| Pronetalol SCHEMBL3203560 | 0.81 | TSHR (0.97) | TSHRCYP1A2MEN1KMT2AHIF1A | |
| Pronetalol SCHEMBL10783519 | 0.81 | TSHR (0.97) | TSHRCYP1A2MEN1KMT2AHIF1A | |
| Pronetalol SCHEMBL14973465 | 0.80 | TSHR (0.94) | TSHRCYP1A2MEN1KMT2AHIF1A | |
| SCHEMBL5661148 | 0.79 | ABCB11 (0.70) | TSHRCYP1A2MAPTTDP1LMNA | |
| SCHEMBL5660959 | 0.79 | ABCB11 (0.70) | TSHRCYP1A2MAPTTDP1LMNA | |
| SCHEMBL5661142 | 0.79 | ABCB11 (0.70) | TSHRCYP1A2MAPTTDP1LMNA | |
| SCHEMBL15087422 | 0.79 | AKR1C3 (0.62) | TSHRCYP1A2MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |