Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278195 | 0.91 | HTR7 (0.55) | HTR7PPARGPPARASIGMAR1KCNA3 | |
| SCHEMBL4587606 | 0.88 | PPARG (0.53) | HTR7PPARGPPARASIGMAR1KCNA3 | |
| SCHEMBL6618898 | 0.87 | HTR7 (0.58) | HTR7PPARGPPARASIGMAR1KCNA3 | |
| SCHEMBL9020738 | 0.86 | HTR7 (0.52) | HTR7PPARGPPARAKCNA3HTR2C | |
| SCHEMBL11282820 | 0.85 | HTR7 (0.57) | HTR7PPARGPPARASIGMAR1KCNA3 | |
| Hydrochloric Acid SCHEMBL10736913 | 0.84 | HTR7 (0.56) | HTR7PPARGPPARASIGMAR1KCNA3 | |
| SCHEMBL10738329 | 0.84 | HTR7 (0.55) | HTR7PPARGPPARASIGMAR1KCNA3 | |
| SCHEMBL4589510 | 0.83 | PPARG (0.64) | HTR7PPARGPPARA | |
| SCHEMBL4587591 | 0.83 | PPARG (0.47) | HTR7PPARGPPARASIGMAR1PARP1 | |
| SCHEMBL4587597 | 0.83 | PPARG (0.47) | HTR7PPARGPPARASIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060179-A1 | Pharmaceutical compositions having anorectic activity | SANOFI S.A. (FR) | 1982-09-15 | — | — | EP | claimed |
| EP-0060179-A1 | Pharmaceutical compositions having anorectic activity | SANOFI S.A. (FR) | 1982-09-15 | — | — | EP | disclosed |