Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 8/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 13/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083308 | 0.90 | AKR1C3 (0.53) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11267327 | 0.88 | ALPG (0.49) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11429362 | 0.87 | ALPG (0.65) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11081254 | 0.87 | ALPG (0.48) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11080644 | 0.87 | KDM4E (0.48) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11080513 | 0.87 | ALPG (0.48) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11297137 | 0.83 | ALPG (0.45) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11076189 | 0.83 | ALPG (0.44) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11272735 | 0.83 | ALPG (0.44) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11266029 | 0.81 | MT-CO2 (0.43) | ALPGPTAFRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011142-A1 | Pyrido (2,1-b) quinazolinones, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | claimed |
| EP-0011142-B1 | PYRIDO (2,1-B) QUINAZOLINONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |
| EP-0011142-A1 | Pyrido (2,1-b) quinazolinones, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |