Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268021 | 0.91 | TSHR (0.38) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL10713783 | 0.88 | TSHR (0.41) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL11278781 | 0.84 | TSHR (0.36) | TSHRALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11273214 | 0.83 | TSHR (0.47) | TSHRIDO1AGXTALDH1A1LMNA | |
| SCHEMBL11574750 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SLC6A2SLC6A3LMNAHCAR2 | |
| SCHEMBL11270991 | 0.82 | IDO1 (0.47) | IDO1AGXTALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL19036955 | 0.81 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1TDP1 | |
| SCHEMBL5934052 | 0.80 | TSHR (0.41) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL11672508 | 0.80 | TSHR (0.41) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL11271261 | 0.79 | TSHR (0.44) | TSHRIDO1AGXTALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332612-A | N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE | GAF CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| US-4102670-A | Beta-halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4102668-A | β-Halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4098601-A | Beta-halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-3985780-A | β-Halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |